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Impact of serum bicarbonate levels on muscle mass and kidney function in pre-dialysis chronic kidney disease patients

Body Composition Assessment
Author
P. Kittiskulnam et al.
Used Parameters : MM, SMMI ALM, SMI, PBF

Publication Year : 2019

Country : Thailand

Journal : American Journal of Nephrology

Background: Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal function among chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscle parameters, nutrition, and renal function in pre-dialysis CKD patients. Methods: This was a randomized, controlled study. CKD stage 3–4 patients with serum HCO 3–< 22 mEq/L were randomized to either receive …
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