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Metabolic and catecholamine response to sympathetic stimulation in early-treated adult male patients with phenylketonuria

Endocrinology
Author
Sumanszki et al.
Used Parameters : PBF, MM
Publication Year : 2020
Country : Hungary
Journal : Hormones
Purpose Defective function of phenylalanine hydroxylase in phenylketonuria (PKU) results in the accumulation of phenylalanine (Phe) and the reduction of tyrosine (Tyr) in the blood, interfering in the normal development and function of organs and tissues in the body. Tyr is the precursor of catecholamines, secreted in response to stress by the adrenal medulla and paraganglia. The aim of this study was to evaluate plasma catecholamine and amino acid response to an escalating series of sympathetic stress tests in PKU patients. Methods …
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