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Isocaloric ketogenic diet in adults with high-grade gliomas: a prospective metabolic study

Foppiani et al.
Used Parameters : PBF, BFM, FFM, TBW, ECW/TBW

Publication Year : 2020

Country : Italy

Journal : Nutrition and Cancer

The use of the ketogenic diet (KD) as an adjuvant therapy in high-grade gliomas (HGG) is supported by preclinical studies, but clinical data on its effects on metabolism are currently lacking. In this study, we describe the effects of a KD on glucose profile, ketonemia, energy metabolism, and nutritional status, in adults affected by HGG. This was a single-arm prospective study. An isocaloric 3: 1 KD was administered for 1 mo. Glucose profile was assessed by using fasting glycemia, insulin, and glycated hemoglobin. To evaluate …
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