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TLR4 receptor D299G/T399I haplotype polymorphism is associated with insulin resistance in obese female subjects

Body Composition Assessment
Sharif et al.
Used Parameters : PBF

Publication Year : 2020

Country : Qatar

Journal : Genes

Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4 D299G/T399I, and its impact on protein expression of TLR4 in obese female subjects. Methodology: A prospective cross-sectional association study was performed on Arab female subjects from Qatar University. The subjects were categorized according to BMI classifications into two groups:“obese; n= 69” and “non-obese; …
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