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Dietary Behaviours May Modulate the Association Between Common MC4R Genetic Variants and Obesity and Its Comorbidities: The 100

Body Composition Assessment
Adamska-Patruno et al.
Used Parameters : BMI, BFM, VFA

Publication Year : 2020

Country : Poland

Journal : Research square

Abstract Background: The MC4R gene harbours one of the strongest susceptibility locus for obesity, and its metabolic consequences. The objective of this study was to analyze whether dietary factors may attenuate the MC4R genotypes effects on obesity and its comorbidities. Methods: In 819 adult participants, genotyped for MC4R SNPs (rs17782313, rs12970134, rs633265, rs1350341) the anthropometric measurements, total body fat, visceral (VAT) and subcutaneous adipose tissue (SAT), blood glucose, insulin, total-, LDL-, HDL-cholesterol …
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