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Relationship between circulating irisin, renal function and body composition in type 2 diabetes

Endocrinology
Author
Jian-Jun Liu et al.
Used Parameters : FFM, %FFM, BFM, PBF

Publication Year : 2013

Country : Singapore

Journal : Journal of Diabetes and its Complications

Aims Chronic kidney disease (CKD) secondary to type 2 diabetes mellitus (T2DM) is associated with multifaceted energy dysmetabolism. We aim to study the relationship between renal function, body composition and irisin, the recently identified myokine which is involved in energy regulation, in T2DM. Methods Circulating irisin and body composition were measured in 365 T2DM subjects across a wide range of renal function. Results Circulating irisin was significantly decreased in T2DM with renal insufficiency (77.4±13.7 …
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