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Assessment of endothelial dysfunction by flow‐mediated dilatation in men on long‐term androgen deprivation therapy for prostate

Cancer/ Palliative treatment
Stephen E. Gilbert et al.
Used Parameters : SMM, BFM, PBF, VFA

Publication Year : 2013

Country : UK

Journal : Experimental Physiology

New Findings• What is the central question of this study? Androgen deprivation therapy (ADT) for prostate cancer has been linked with increased cardiovascular risk, but the mechanisms are unclear. Is there evidence that endothelial dysfunction, as evidenced by reduced flow‐mediated dilatation (FMD), is associated with ADT?• What is the main finding and its importance? Reduction in FMD with preservation of glyceryl trinitrate‐mediated dilatation indicates endothelial dysfunction in men with prostate cancer on long‐term ADT …
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