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Association of the anti-angiogenic factor secreted protein and rich in cysteine (SPARC) with vascular complications among Chine

Moh MC et al.
Used Parameters : .

Publication Year : 2016

Country : Singapore

Journal : Journals of Diabetes and its Complications

Aims This study evaluated the association of the anti-angiogenic SPARC with known angiogenesis-associated factors and diabetes-related micro-and macro-vascular complications in a Singapore Chinese cohort with type 2 diabetes (T2DM). Methods Plasma SPARC was measured by immunoassay in 438 T2DM adults (mean age: 58±11 years). Results Higher SPARC levels in subjects stratified by SPARC tertiles displayed decreased pro-angiogenic adiponectin, osteopontin, vascular cell adhesion molecule (VCAM)-1 and …
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