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Advanced glycation end‐products are a risk for muscle weakness in Japanese patients with type 1 diabetes

Endocrinology
Author
Mori H et al.
Used Parameters : SMM, SMI

Publication Year : 2016

Country : Japan

Journal : Journal of Diabetes Investigation

Accumulation of advanced glycation end‐products (AGE s) is thought to contribute to muscle weakness in a diabetic animal model. Skin autofluorescence is a proposed marker for accumulation of AGE s in the skin. We aimed to investigate the relationship between AGE s accumulation, sarcopenia and muscle function of Japanese patients with type 1 diabetes. A total of 36 patients with type 1 diabetes participated in the present cross‐sectional study. Sarcopenia parameters (skeletal muscle mass index and knee extension strength) were …
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