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Anamorelin (ONO-7643) in Japanese patients with non-small cell lung cancer and cachexia: results of a randomized phase 2 trial

Body Composition Assessment
Author
Takayama K et al.
Used Parameters : Body composition
Publication Year : 2016
Country : Japan
Journal : Support Care Cancer
Purpose Cancer cachexia is characterized by decreased body weight (mainly lean body mass [LBM]) and negatively impacts quality of life (QOL) and prognosis. Anamorelin (ONO-7643) is a novel selective ghrelin receptor agonist under development for treating cancer cachexia. Methods In this double-blind, exploratory phase 2 trial, we examined the efficacy and safety of anamorelin in Japanese patients (n= 181) with non-small cell lung cancer (NSCLC) and cancer cachexia (≥ 5% weight loss within the previous 6 months). The …
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