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Leukocyte and skeletal muscle telomere length and body composition in monozygotic twin pairs discordant for long-term hormone r

Body Composition Assessment
Sillanpää E et al.
Used Parameters : FFM, PBF

Publication Year : 2017

Country : Finland

Journal : Twin Research and Human Genetics

Estrogen-based hormone replacement therapy (HRT) may be associated with deceleration of cellular aging. We investigated whether long-term HRT has effects on leukocyte (LTL) or mean and minimum skeletal muscle telomere length (SMTL) in a design that controls for genotype and childhood environment. Associations between telomeres, body composition, and physical performance were also examined. Eleven monozygotic twin pairs (age 57.6±1.8 years) discordant for HRT were studied. Mean duration of HRT use was 7.3±3.7 …
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