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Canagliflozin reduces epicardial fat in patients with type 2 diabetes mellitus

Endocrinology
Author
S Yagi et al.
Used Parameters : SMM

Publication Year : 2017

Country : Japan

Journal : Diabetology & Metabolic Syndrome

It is unknown whether canagliflozin, a selective sodium glucose co-transporter 2 inhibitor, reduces epicardial adipose tissue (EAT) thickness, which is associated with insulin resistance and is a risk factor for coronary artery disease. We administered 100 mg of canagliflozin for 6 months to 13 patients with type 2 diabetes mellitus. We evaluated glycemic control, visceral adipose tissue (VAT) area and subcutaneous adipose tissue (SAT) area, and skeletal muscle mass by using impedance methods, and EAT thickness by using …
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