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Does metformin treatment during pregnancy modify the future metabolic profile in women with PCOS?

Underdal et al
Used Parameters : Muscle Mass, BFM, PBF

Publication Year : 2018

Country : Norway

Journal : Journal of Clinical Endocrinology & Metabolism

Context Worldwide, metformin is prescribed to improve pregnancy outcome in polycystic ovary syndrome (PCOS). Metformin may also benefit future health by modulating increased metabolic stress during pregnancy. Objective To investigate whether metformin during pregnancy modified future metabolic health in women with PCOS. Design Follow-up study of a randomized controlled trial that compared metformin with placebo in women with PCOS. Mean follow-up period was 7.7 years (range, 5 to 11 years). Setting Three university …
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