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Role of serum myostatin in the association between hyperinsulinemia and muscle atrophy in Japanese obese patients

M Tanaka et al.
Used Parameters : SMM, BFM, PBF

Publication Year : 2018

Country : Japan

Journal : Diabetes Research and Clinical Practice

Aims The protein myostatin is a member of the transforming growth factor β superfamily. This is mainly expressed in skeletal muscle and negatively regulates skeletal muscle growth. The present study aimed to elucidate the associations among circulating myostatin level, skeletal muscle mass, and metabolic profiles in Japanese obese patients. Methods Japanese obese outpatients (n= 74) were enrolled. We measured clinical parameters, quantified serum myostatin levels, and examined their associations in a cross-sectional manner. Results Both …
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