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Advanced glycation end product accumulation is associated with low skeletal muscle mass, weak muscle strength, and reduced bone

Lifestyle Disease
Tabara Y et al
Used Parameters : SMI

Publication Year : 2018

Country : Japan

Journal : The Journals of Gerontology

Background The accumulation of advanced glycation end product (AGE) might exert deleterious effects on musculoskeletal properties. Our study aims to clarify this possible association in a large general population. Methods This study investigated a general population of 9,203 patients (mean age, 57.8 years). Skeletal muscle mass was measured by bioelectrical impedance analysis, whereas accumulation of AGEs was assessed by skin autofluorescence (SAF-AGE). The muscle strength of upper and lower limbs and usual gait …
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