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Altered autonomic reactivity during lower body negative pressure in end-stage renal disease

Nephrology
Author
Ye et al.
Used Parameters : ECW, ICW

Publication Year : 2019

Country : USA

Journal : The American Journal of the Medical Sciences

Background End stage renal disease (ESRD) is characterized by autonomic dysfunction. During orthostatic stress, sympathetic (SNS) activity increases and parasympathetic (PNS) activity decreases to maintain arterial blood pressure (BP). We hypothesized that ESRD patients have impaired ability to adjust cardiac SNS and PNS activity during orthostasis, which could contribute to increased blood pressure variability, orthostatic intolerance and falls. Methods We measured beat-to-beat BP and Electrocardiography at baseline and …
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