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The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet–induced changes among overweight

Min Ho Cha et al.
Used Parameters : FFM, BFM, PBF, WHR

Publication Year : 2006

Country : Korea

Journal : Metabolism

Responses to energy restriction tend to vary within the population because of genetic differences. In this study, we have genotyped 6 uncoupling protein 3 (UCP-3) polymorphisms (− 55C/T, Int2-143G/C, Tyr99Tyr, Int3-47G/A, Int4-498C/T, and Tyr210Tyr) among 214 overweight Korean female subjects recruited from an obesity clinic. Three major haplotypes, identified with frequencies in excess of 0.04, were constructed from 6 single nucleotide polymorphisms. Association studies were then undertaken, involving the …
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