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The impact of antihypertensive drug therapy on endotoxemia in elderly patients with chronic kidney disease

Nephrology
Author
Stephen G. John et al.
Used Parameters : TBW

Publication Year : 2011

Country : UK

Journal : Clinical Journal of the American Society of Nephrology

Background and objectives Endotoxin (ET) is recognized to cause adverse effects on cardiovascular (CV) structure. Circulatory translocation of gut bacterial ET is described in heart failure. Chronic kidney disease (CKD) is common in older people and aggressive BP control is the cornerstone of management. We therefore studied ET after improvement of the overall CV milieu with introduction of optimized antihypertensive therapy (AHT). Design, setting, participants, & measurements We recruited 40 hypertensive nondiabetic patients (≥ …
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