RESEARCH DATABASE

InBody Scholar

InBody continues to work closely with academic researchers on a global scale to develop more in-depth clinical applications of body composition. With our long history in the industry, we provide more than 6,000 research publications. Research title with ★ indicates InBody recommended paper.

Printable list of studies

Download Annual Studies PDF

The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension

Body Composition Assessment
Author
Ewout J Hoorn et al.
Used Parameters : Not mentioned
Publication Year : 2011
Country : USA
Journal : Nature Medicine
Calcineurin inhibitors (CNIs) are immunosuppressive drugs that are used widely to prevent rejection of transplanted organs and to treat autoimmune disease. Hypertension and renal tubule dysfunction, including hyperkalemia, hypercalciuria and acidosis, often complicate their use 1, 2. These side effects resemble familial hyperkalemic hypertension, a genetic disease characterized by overactivity of the renal sodium chloride cotransporter (NCC) and caused by mutations in genes encoding WNK kinases. We hypothesized that CNIs induce …
Full text
List
Powered by KBoard